Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.72 |
| ▸ | TSHR | P16473 | 1/20 | 0.72 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9173912 | 0.94 | ALDH1A1 (0.71) | ALDH1A1TSHRSLC6A3OPRL1GRIN2B | |
| SCHEMBL9296560 | 0.89 | ALDH1A1 (0.74) | ALDH1A1TSHRSLC6A3OPRL1GRIN2B | |
| SCHEMBL8967036 | 0.88 | ALDH1A1 (0.63) | ALDH1A1TSHRSLC6A3HTR1ALMNA | |
| SCHEMBL8967698 | 0.88 | ALDH1A1 (0.63) | ALDH1A1TSHRSLC6A3OPRL1GRIN2B | |
| SCHEMBL11870408 | 0.88 | ALDH1A1 (0.72) | ALDH1A1TSHRSLC6A3OPRL1OPRM1 | |
| SCHEMBL9710583 | 0.87 | TSHR (0.78) | ALDH1A1TSHRSLC6A3OPRL1OPRM1 | |
| SCHEMBL11861506 | 0.85 | ALDH1A1 (0.68) | ALDH1A1TSHRSLC6A3OPRL1OPRM1 | |
| SCHEMBL11867863 | 0.85 | ALDH1A1 (0.68) | ALDH1A1TSHRSLC6A3OPRL1OPRM1 | |
| SCHEMBL11872237 | 0.85 | ALDH1A1 (0.68) | ALDH1A1TSHRSLC6A3OPRL1OPRM1 | |
| SCHEMBL11867116 | 0.84 | ALDH1A1 (1.00) | ALDH1A1TSHRSLC6A3OPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992018480-A1 | 1,3,4-TRISUBSTITUTED PIPERIDINE DERIVATIVES, THEIR PRODUCTION AND USE | BASF AKTIENGESELLSCHAFT (DE) | 1992-10-29 | — | — | WO | disclosed |