Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710802 | 1.00 | KMT2A (0.40) | KMT2ATSHRCYP3A4CYP1A2CYP2D6 | |
| SCHEMBL10333088 | 0.81 | KMT2A (0.42) | KMT2ATSHRCYP3A4CYP1A2CYP2D6 | |
| SCHEMBL10333089 | 0.81 | KMT2A (0.42) | KMT2ATSHRCYP3A4CYP1A2CYP2D6 | |
| SCHEMBL8953655 | 0.81 | RIPK1 (0.35) | TSHRLMNAADRA2AADRA2CHIF1A | |
| SCHEMBL11766832 | 0.81 | MMP8 (0.40) | KMT2ATSHRCYP3A4CYP1A2CYP2D6 | |
| SCHEMBL11766835 | 0.81 | MMP8 (0.40) | KMT2ATSHRCYP3A4CYP1A2CYP2D6 | |
| SCHEMBL7309316 | 0.71 | KMT2A (0.44) | KMT2ATSHRCYP3A4CYP1A2CYP2D6 | |
| SCHEMBL1526022 | 0.71 | KMT2A (0.64) | KMT2ATSHRLMNAMEN1PTGS1 | |
| SCHEMBL11776768 | 0.70 | KMT2A (0.48) | KMT2ATSHRCYP3A4CYP1A2CYP2D6 | |
| SCHEMBL9711394 | 0.70 | KMT2A (0.37) | KMT2ATSHRCYP3A4CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0290682-B1 | HERBICIDAL 4,5-DIHYDRO-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE DERIVATIVES | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-07-01 | — | — | EP | claimed |
| EP-0290682-A2 | Herbicidal 4,5-dihydro-1H-1,2,4-triazole-3-carboxamide derivatives | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-11-17 | — | — | EP | claimed |
| EP-0290682-B1 | HERBICIDAL 4,5-DIHYDRO-1H-1,2,4-TRIAZOLE-3-CARBOXAMIDE DERIVATIVES | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1992-07-01 | — | — | EP | disclosed |
| US-4897106-A | Derivative of 4,5-dihydro-1H-1,2,4-triazole-3-carboxamide, and herbicidal composition containing the derivative | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1990-01-30 | — | — | US | disclosed |
| EP-0290682-A2 | Herbicidal 4,5-dihydro-1H-1,2,4-triazole-3-carboxamide derivatives | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-11-17 | — | — | EP | disclosed |