Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28144251 | 0.72 | ASAH1 (0.52) | ALDH1A1 | |
| SCHEMBL28352839 | 0.71 | KMT2A (0.47) | KMT2ATSHRCA12CA7CA9 | |
| SCHEMBL27471813 | 0.71 | CES2 (0.44) | KMT2ATSHRMEN1ALDH1A1HPGD | |
| SCHEMBL9710799 | 0.70 | KMT2A (0.40) | KMT2ATSHRMEN1ALDH1A1CYP3A4 | |
| SCHEMBL9710802 | 0.70 | KMT2A (0.40) | KMT2ATSHRMEN1ALDH1A1CYP3A4 | |
| SCHEMBL1526022 | 0.67 | KMT2A (0.64) | KMT2ATSHRMEN1ALDH1A1 | |
| SCHEMBL11776768 | 0.66 | KMT2A (0.48) | KMT2ATSHRGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL496468 | 0.65 | KMT2A (0.50) | KMT2ATSHRHPGDCYP3A4CYP1A2 | |
| SCHEMBL10350843 | 0.65 | LMNA (0.42) | KMT2AMEN1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL29000290 | 0.63 | MAPT (0.48) | KMT2ATSHRMEN1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992019588-A1 | NEW AMIDRAZONE DERIVATES, PROCESS FOR PRODUCING THE SAME AND THEIR USE AS LIPOXYGENASE INHIBITORS | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1992-11-12 | — | — | WO | disclosed |