SCHEMBL9710882

SCHEMBL9710882

CC(C)(C)[Si](C)(C)OC(CC(=O)O)c1ncnn1C(c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
FFAR1 O14842 2/20 0.31
MAPK1 P28482 1/20 0.31
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9710874 0.85
SCHEMBL9541851 0.70 ATM (0.30) ATM
SCHEMBL9247999 0.70 ALDH1A1 (0.39)
SCHEMBL28608238 0.69 CNR2 (0.41) CYP2C19FFAR1
SCHEMBL28608240 0.67 FFAR1 (0.51) FFAR1
SCHEMBL18704145 0.66 FFAR1 (0.47) CYP2C19FFAR1ATM
SCHEMBL18704147 0.66 FFAR1 (0.47) CYP2C19FFAR1ATM
Phosphonic Acid SCHEMBL9541854 0.66 LMNA (0.36) ATM
SCHEMBL9710889 0.66
SCHEMBL6525612 0.66 ATM (0.39) ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992019629-A1 TRIAZOLE COMPOUNDS JAPAT LTD. (CH) 1992-11-12 WO disclosed