Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 2/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | F10 | P00742 | 2/20 | 0.40 |
| ▸ | CMA1 | P23946 | 9/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9710401 | 0.90 | ACE (0.41) | ACEF10CMA1XIAPF2 | |
| SCHEMBL9710492 | 0.90 | F10 (0.48) | ACEF10F2PRSS1 | |
| Iodide SCHEMBL9710506 | 0.89 | F10 (0.48) | ACEF10F2PRSS1 | |
| SCHEMBL9710466 | 0.80 | CTSG (0.42) | P2RX7CMA1F2 | |
| SCHEMBL7023692 | 0.75 | F10 (0.56) | F10F2 | |
| SCHEMBL17081787 | 0.74 | ACE (0.56) | ACECMA1F2PRSS1 | |
| SCHEMBL10053455 | 0.74 | ACE (0.56) | ACECMA1F2PRSS1 | |
| SCHEMBL10021917 | 0.74 | ACE (0.56) | ACECMA1F2PRSS1 | |
| SCHEMBL9710711 | 0.72 | KMT2A (0.40) | TACR1F10F2PRSS1 | |
| SCHEMBL9710484 | 0.71 | F2 (0.54) | F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016549-A1 | PARASUBSTITUTED PHENYLALANINE DERIVATES | PENTAPHARM AG (CH) | 1992-10-01 | — | — | WO | disclosed |