Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PLAT | P00750 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 2/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954993 | 0.81 | CASR (0.41) | ALDH1A1TACR1F2PRSS1F10 | |
| SCHEMBL9710478 | 0.78 | DPP4 (0.42) | KMT2AMEN1TACR1F2PLAU | |
| Iodide SCHEMBL9710508 | 0.76 | F10 (0.51) | F2PRSS1PLAUF10 | |
| SCHEMBL9710643 | 0.74 | MMP8 (0.40) | KMT2AALDH1A1KDM4ECASRLMNA | |
| SCHEMBL9710558 | 0.74 | MMP8 (0.38) | KMT2AKDM4EF10CASRLMNA | |
| SCHEMBL8954708 | 0.74 | CASR (0.39) | TACR1F2PRSS1PLAUF10 | |
| SCHEMBL8954772 | 0.74 | F10 (0.40) | TACR1F2PLAUF10CASR | |
| SCHEMBL9710885 | 0.72 | ACE (0.43) | TACR1F2PRSS1F10 | |
| SCHEMBL7023692 | 0.72 | F10 (0.56) | F2PLAUF10 | |
| SCHEMBL9664400 | 0.72 | ALDH1A1 (0.47) | ALDH1A1F2PRSS1PLAUF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016549-A1 | PARASUBSTITUTED PHENYLALANINE DERIVATES | PENTAPHARM AG (CH) | 1992-10-01 | — | — | WO | disclosed |