Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | PTPRF | P10586 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9099602 | 0.85 | HSD11B1 (0.38) | PTGS2PTGDR2HSD11B1MEN1KMT2A | |
| SCHEMBL4279326 | 0.83 | PTGS2 (0.46) | PTGS2PTGDR2HSD11B1PTGES2ALDH1A1 | |
| SCHEMBL27952944 | 0.82 | PTGS2 (0.45) | PTGS2PTGDR2HSD11B1PTGES2ALDH1A1 | |
| SCHEMBL778291 | 0.78 | HSD11B1 (0.36) | PTGS2PTGDR2HSD11B1PTGES2MEN1 | |
| SCHEMBL29219511 | 0.75 | HSD11B1 (0.48) | PTGS2HSD11B1LMNACA1CA2 | |
| SCHEMBL9097473 | 0.75 | HSD11B1 (0.48) | PTGS2HSD11B1LMNACA1CA2 | |
| SCHEMBL9098609 | 0.75 | HSD11B1 (0.41) | PTGS2PTGDR2HSD11B1ALDH1A1LMNA | |
| SCHEMBL16712192 | 0.72 | MEN1 (0.44) | PTGS2HSD11B1MEN1KMT2AALDH1A1 | |
| SCHEMBL8368970 | 0.72 | HSD11B1 (0.41) | HSD11B1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL16816963 | 0.71 | TSHR (0.59) | MEN1KMT2AALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0254937-B1 | HYDROFORMYLATION USING LOW VOLATILE/ORGANIC SOLUBLE PHOSPHINE LIGANDS | UNION CARBIDE CORPORATION (US) | 1992-03-25 | — | — | EP | disclosed |
| EP-0254937-A2 | Hydroformylation using low volatile/organic soluble phosphine ligands | UNION CARBIDE CORPORATION (US) | 1988-02-03 | — | — | EP | disclosed |