Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TTR | P02766 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL778291 | 0.89 | HSD11B1 (0.36) | HSD11B1CA1CA2PTGS2LMNA | |
| SCHEMBL4279326 | 0.87 | PTGS2 (0.46) | HSD11B1PTGS2LMNAMYCMAPT | |
| SCHEMBL27952944 | 0.86 | PTGS2 (0.45) | HSD11B1PTGS2LMNAMYCMAPT | |
| SCHEMBL9710892 | 0.85 | PTGS2 (0.35) | HSD11B1CA1CA2PTGS2LMNA | |
| SCHEMBL9097473 | 0.85 | HSD11B1 (0.48) | HSD11B1CA1CA2PTGS2LMNA | |
| SCHEMBL29219511 | 0.85 | HSD11B1 (0.48) | HSD11B1CA1CA2PTGS2LMNA | |
| SCHEMBL8368970 | 0.81 | HSD11B1 (0.41) | HSD11B1LMNAMYCMAPTTTR | |
| SCHEMBL9098064 | 0.79 | ACHE (0.36) | CA1CA2LMNACHRNB4CHRNA3 | |
| SCHEMBL9098609 | 0.78 | HSD11B1 (0.41) | HSD11B1PTGS2LMNAMAPTPTGDR2 | |
| SCHEMBL28444015 | 0.78 | MYC (0.41) | HSD11B1CA1CA2LMNAMYC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5489501-A | MIXTURES OF TWO COORDINATION COMPOUNDS WHICH REACT TO FORM NEW COORDINATION COMPOUND WHILE CAUSING VISIBLE COLOR CHANGES | RICOH COMPANY, LTD. (JP) | 1996-02-06 | — | — | US | disclosed |
| US-5446011-A | Imagewise coloring when heating; mixture of n-substituted indole, aromatic polyhydroxy compound, carbonyl compound and an acid | RICOH COMPANY, LTD. (JP) | 1995-08-29 | — | — | US | disclosed |