Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.46 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.46 |
| ▸ | KMO | O15229 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7946402 | 0.85 | KMT2A (0.43) | KMT2AKDM4EMEN1MKNK1MKNK2 | |
| SCHEMBL7957097 | 0.85 | KMT2A (0.43) | KMT2AKDM4EMEN1MKNK1MKNK2 | |
| SCHEMBL7946425 | 0.85 | KDM4E (0.49) | KMT2AKDM4EMEN1MKNK1MKNK2 | |
| SCHEMBL1514634 | 0.84 | KMT2A (0.76) | KMT2AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL9066017 | 0.83 | KMT2A (0.70) | KMT2AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL9065383 | 0.83 | KMT2A (0.73) | KMT2AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL7946379 | 0.80 | CYP11B2 (0.42) | KMT2AKDM4EMEN1MKNK1MKNK2 | |
| SCHEMBL7953616 | 0.80 | KMT2A (0.43) | KMT2AKDM4EMEN1MKNK1MKNK2 | |
| SCHEMBL9711224 | 0.78 | KMT2A (0.70) | KMT2AKDM4EMEN1ALDH1A1LMNA | |
| SCHEMBL7954909 | 0.78 | MKNK1 (0.41) | KMT2AMEN1MKNK1MKNK2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0479951-A1 | BIS-ACYLOXYMETHYL DERIVATIVES | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1992-04-15 | — | — | EP | disclosed |
| WO-1991000093-A1 | BIS-ACYLOXYMETHYL DERIVATIVES | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1991-01-10 | — | — | WO | disclosed |