SCHEMBL9711010

SCHEMBL9711010

c1cc2c(cc1CCc1ccc3c(c1)CC3)CC2

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 6/20 0.39
DRD3 P35462 6/20 0.39
PLAU P00749 1/20 0.39
RXRB P28702 1/20 0.36
GRIN2B Q13224 2/20 0.36
MLNR O43193 2/20 0.36
CETP P11597 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9720050 0.92 TSHR (0.46) RXRBCETP
SCHEMBL16682944 0.85 ALDH1A1 (0.42) DRD2DRD3PLAURXRBGRIN2B
SCHEMBL17188629 0.82 CYP2D6 (0.42) DRD2DRD3GRIN2BMLNR
SCHEMBL8184437 0.82 DRD2 (0.50) DRD2DRD3GRIN2B
SCHEMBL22369581 0.80 GRIN2B (0.44) GRIN2B
SCHEMBL21947364 0.80 MLNR (0.33) RXRBMLNR
SCHEMBL22685045 0.80 GRIN2B (0.38) GRIN2BMLNR
SCHEMBL21947365 0.80 CHRM2 (0.35) RXRBMLNR
SCHEMBL10169204 0.80 GRIN2B (0.38) DRD2DRD3PLAUGRIN2BMLNR
SCHEMBL12379477 0.80 DRD2 (0.36) DRD2DRD3GRIN2BMLNRCETP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0195785-B1 POLYMERIC COMPOSITION DERIVED FROM POLY(ARYLCYCLOBUTENES) AND A PROCESS FOR PREPARING SAID POLYMERIC COMPOSITION THE DOW CHEMICAL COMPANY (US) 1992-03-18 EP disclosed