Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | RXRB | P28702 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711010 | 0.92 | DRD2 (0.39) | RXRBCETP | |
| SCHEMBL8184437 | 0.89 | DRD2 (0.50) | TSHRLMNANPC1RAB9A | |
| SCHEMBL3453086 | 0.86 | HPGD (0.40) | TSHRRXRBADRA2AADRA2BADRA2C | |
| SCHEMBL17186185 | 0.86 | TAAR1 (0.47) | ADRA2AADRA2BADRA2CALOX15HSD17B10 | |
| SCHEMBL8853672 | 0.86 | ALDH1A1 (0.48) | TSHRRXRBADRA2AADRA2BADRA2C | |
| SCHEMBL30496730 | 0.86 | TAAR1 (0.47) | ADRA2AADRA2BADRA2CALOX15HSD17B10 | |
| Hydrochloric Acid SCHEMBL5157753 | 0.84 | TDP1 (0.48) | ADRA2AADRA2BADRA2CALOX15HSD17B10 | |
| SCHEMBL5079011 | 0.84 | TAAR1 (0.45) | RXRBADRA2AADRA2BADRA2CALOX15 | |
| SCHEMBL19158886 | 0.84 | NPC1 (0.45) | RXRBADRA2AADRA2BADRA2CCETP | |
| SCHEMBL3452332 | 0.84 | RXRB (0.41) | TSHRRXRBCETPALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5081099-A | A tetrahydronaphthalene sensitizer as antifogging agent; storage stability | ADEKA ARGUS CHEMICAL CO., LTD. (JP) | 1992-01-14 | — | — | US | disclosed |