Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711260 | 0.98 | SOS1 (0.30) | SOS1 | |
| SCHEMBL9711255 | 0.74 | SOS1 (0.33) | SOS1 | |
| SCHEMBL6885886 | 0.73 | CA1 (0.36) | — | |
| SCHEMBL5270799 | 0.72 | ALDH1A1 (0.41) | — | |
| SCHEMBL10344609 | 0.72 | CES2 (0.42) | — | |
| SCHEMBL7170546 | 0.71 | ALDH1A1 (0.37) | — | |
| SCHEMBL1583684 | 0.70 | CES2 (0.40) | — | |
| SCHEMBL29590125 | 0.70 | CES2 (0.40) | — | |
| SCHEMBL6890747 | 0.70 | CA1 (0.33) | — | |
| SCHEMBL28831953 | 0.70 | HDAC1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153227-A | Treatment of diabetes and galactosemia complications | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-10-06 | — | — | US | disclosed |
| EP-0304190-B1 | (ARYLSULPHONYL)NITROMETHANES, PROCESS FOR THEIR PREPARATION AND USE IN PHARMACEUTICAL COMPOSITIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-07-08 | — | — | EP | disclosed |
| EP-0304190-A1 | (Arylsulphonyl)nitromethanes, process for their preparation and use in pharmaceutical compositions | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-02-22 | — | — | EP | disclosed |