SCHEMBL5270799

SCHEMBL5270799

Cc1cc(C)cc(S(=O)O)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
TPMT P51580 1/20 0.40
TSHR P16473 3/20 0.36
ACHE P22303 2/20 0.33
SELL P14151 1/20 0.33
SELP P16109 1/20 0.33
SELE P16581 1/20 0.33
PRSS1 P07477 1/20 0.33
PRSS2 P07478 1/20 0.33
C1S P09871 1/20 0.33
PRSS3 P35030 1/20 0.33
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
CYP3A4 P08684 2/20 0.32
MAPK1 P28482 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ERN1 O75460 1/20 0.32
HSP90AA1 P07900 1/20 0.31
CCR6 P51684 1/20 0.31
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14198480 0.80 TPMT (0.61) ALDH1A1TPMTTSHRSELLSELP
SCHEMBL12706258 0.79 PGK1 (0.40) RXRARXRBPGK1PGK2
SCHEMBL6885886 0.78 CA1 (0.36)
SCHEMBL6890747 0.76 CA1 (0.33)
SCHEMBL30891540 0.75 ACHE (0.48) ALDH1A1TSHRACHEMAPK1
SCHEMBL4457937 0.75 ACHE (0.48) ALDH1A1TSHRACHEMAPK1
SCHEMBL27507877 0.75 ALDH1A1 (0.50) ALDH1A1TPMTTSHRACHESELL
SCHEMBL8601596 0.74 THRB (0.32) ALDH1A1TSHRCYP3A4
SCHEMBL22305457 0.74 SMN1; SMN2 (0.34) ALDH1A1MAPK1
SCHEMBL7521244 0.74 ACHE (0.46) ALDH1A1TSHRACHEMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4116282-A1 METHOD FOR PRODUCING MONO-CROSS-COUPLED AROMATIC COMPOUND HAVING LEAVING GROUP National University Corporation Hokkaido University (JP) 2023-01-11 EP disclosed
US-20150265964-A1 GAS SEPARATION COMPOSITE MEMBRANE, GAS SEPARATION MODULE, GAS SEPARATION APPARATUS, GAS SEPARATION METHOD, AND METHOD OF PRODUCING GAS SEPARATION COMPOSITE MEMBRANE FUJIFILM CORPORATION (JP) 2015-09-24 US disclosed
EP-1459726-B1 ADHESIVES FOR DENTAL USE TOKUYAMA CORP (JP) 2013-10-02 EP disclosed
US-20130161936-A1 Photographic Paper FUJIFILM MANUFACTURING EUROPE B.V. (GB) 2013-06-27 US disclosed
US-7556918-B2 Color photographic films comprising support having color developable light sensitive silver halide emulsion layers and color dye-forming couplers, used for high speed print reproduction; storage stability FUJIFILM CORPORATION (JP) 2009-07-07 US disclosed
US-20080113305-A1 SILVER HALIDE COLOR PHOTOGRAPHIC LIGHT-SENSITIVE MATERIAL FUJIFILM CORPORATION 2008-05-15 US disclosed
EP-1431315-B1 Photopolymerization initiator and photopolymerizable composition TOKUYAMA CORP (JP) 2007-10-17 EP disclosed
US-7244550-B2 Silver halide color photographic photosensitive material FUJIFILM CORPORATION (JP) 2007-07-17 US disclosed
US-7229749-B2 Silver halide photographic emulsion and silver halide photosensitive material using thereof FUJIFILM CORPORATION (JP) 2007-06-12 US disclosed
US-7196194-B2 Dye-forming coupler, silver halide photographic light-sensitive material and azomethine dye compound FUJI PHOTO FILM CO., LTD (JP) 2007-03-27 US disclosed
US-7041714-B2 Dental adhesive TOKUYAMA CORPORATION (JP) 2006-05-09 US disclosed
US-20040186195-A1 Photopolymerization initiator and photopolymerizable composition TOKUYAMA CORPORATION (JP) 2004-09-23 US disclosed
EP-1459726-A1 ADHESIVES FOR DENTAL USE TOKUYAMA CORPORATION (JP) 2004-09-22 EP disclosed
CN-1513884-A Photopolymerization initiator and composition capable of photopolymerization 株式会社德山 2004-07-21 CN disclosed
EP-1431315-A2 Photopolymerization initiator and photopolymerizable composition Tokuyama Corporation (JP) 2004-06-23 EP disclosed
US-20040077746-A1 Adhesives for dental use TOKUYAMA CORPORATION (JP) 2004-04-22 US disclosed
US-4602084-A Monoazo dyes containing a 4-substituted-2-azo-1,1'-diphenylsulfone component CIBA-GEIGY CORPORATION (US) 1986-07-22 US disclosed
EP-0101408-B1 MONOAZO DYESTUFFS, THEIR PREPARATION AND THEIR USE CIBA-GEIGY AG (CH) 1986-05-07 EP disclosed
EP-0101408-A1 Monoazo dyestuffs, their preparation and their use CIBA-GEIGY AG (CH) 1984-02-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040077746-A1 Adhesives for dental use ICAM1, CDH1, VCAM1 ALDH1A1 242/4885TPMT 1737/4885TSHR 3922/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.