Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | PHLPP2 | Q6ZVD8 | 4/20 | 0.42 |
| ▸ | TYR | P14679 | 2/20 | 0.42 |
| ▸ | ATIC | P31939 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711525 | 1.00 | RPS6KA3 (0.50) | RPS6KA3CYP2C9CYP2C19HSD17B10GLO1 | |
| SCHEMBL13604796 | 0.78 | RPS6KA3 (0.38) | RPS6KA3CYP2C9CYP2C19HSD17B10GLO1 | |
| SCHEMBL29378452 | 0.77 | EGFR (0.69) | RPS6KA3CYP2C9CYP2C19HSD17B10GLO1 | |
| SCHEMBL112101 | 0.77 | EGFR (0.69) | RPS6KA3CYP2C9CYP2C19HSD17B10GLO1 | |
| SCHEMBL112102 | 0.77 | EGFR (0.69) | RPS6KA3CYP2C9CYP2C19HSD17B10GLO1 | |
| SCHEMBL28093072 | 0.76 | ALOX5 (0.51) | HSD17B10TYREGFRLMNAMEN1 | |
| SCHEMBL14563174 | 0.76 | POLB (0.44) | RPS6KA3CYP2C9CYP2C19HSD17B10GLO1 | |
| SCHEMBL144372 | 0.76 | EGFR (0.67) | RPS6KA3CYP2C9CYP2C19HSD17B10GLO1 | |
| SCHEMBL144370 | 0.76 | EGFR (0.67) | RPS6KA3CYP2C9CYP2C19HSD17B10GLO1 | |
| SCHEMBL4842755 | 0.74 | RPS6KA3 (0.55) | RPS6KA3CYP2C9CYP2C19HSD17B10GLO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017550-A1 | BIODEGRADABLE AZO DYES | IDAHO RESEARCH FOUNDATION, INC. (US) | 1992-10-15 | — | — | WO | disclosed |