Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPD | P32754 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711511 | 0.84 | SMN1; SMN2 (0.43) | HPDALDH1A1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9711550 | 0.82 | ALDH1A1 (0.39) | HPDPKMMAPTALDH1A1MEN1 | |
| SCHEMBL9133822 | 0.82 | HPD (0.70) | HPDPKMMAPTALDH1A1MEN1 | |
| SCHEMBL9711546 | 0.80 | HPD (0.61) | HPDPKMMAPTALDH1A1MEN1 | |
| SCHEMBL9711612 | 0.80 | HPD (0.64) | HPDPKMSTAT3MAPTALDH1A1 | |
| SCHEMBL2460810 | 0.79 | HPD (0.65) | HPDPKMSTAT3MAPTALDH1A1 | |
| SCHEMBL9137621 | 0.78 | HPD (0.74) | HPDPKMMAPTALDH1A1MEN1 | |
| SCHEMBL10377513 | 0.78 | HPD (0.64) | HPDPKMMAPTALDH1A1MEN1 | |
| SCHEMBL31388680 | 0.76 | HPD (0.64) | HPDPKMMAPTALDH1A1MEN1 | |
| Nitisinone SCHEMBL338795 | 0.76 | HPD (1.00) | HPDPKMMAPTALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |