Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPD | P32754 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711550 | 0.85 | ALDH1A1 (0.39) | SMN1; SMN2POLBHPDLMNAALDH1A1 | |
| SCHEMBL9711688 | 0.84 | HPD (0.60) | CYP2C19HPDCYP1A2CYP3A4FLT1 | |
| SCHEMBL9240067 | 0.81 | HPD (0.46) | SMN1; SMN2CYP2C19POLBHPDHPGD | |
| SCHEMBL9711611 | 0.81 | HPD (0.49) | SMN1; SMN2CYP2C19HPDHPGDCYP1A2 | |
| SCHEMBL998548 | 0.80 | SMN1; SMN2 (0.43) | SMN1; SMN2CYP2C19POLBHPDHPGD | |
| SCHEMBL9871935 | 0.79 | SMN1; SMN2 (0.48) | SMN1; SMN2CYP2C19POLBHPDHPGD | |
| SCHEMBL9711504 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2CYP2C19POLBHPDHPGD | |
| SCHEMBL1132003 | 0.78 | POLB (0.45) | SMN1; SMN2CYP2C19POLBHPDHPGD | |
| SCHEMBL9229472 | 0.75 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP2C19POLBHPDHPGD | |
| SCHEMBL9814693 | 0.75 | SMN1; SMN2 (0.44) | SMN1; SMN2CYP2C19POLBHPDHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5114461-A | Herbicides | MAY & BAKER LIMITED (GB) | 1992-05-19 | — | — | US | disclosed |
| EP-0278742-A2 | Cyclic diones | MAY & BAKER LIMITED (GB) | 1988-08-17 | — | — | EP | disclosed |