Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 6/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 6/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 6/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | PTGIR | P43119 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9585535 | 0.88 | ALDH1A1 (0.44) | POLBSMN1; SMN2GLAALDH1A1ADRA2C | |
| SCHEMBL9711860 | 0.83 | PKM (0.51) | ALDH1A1LMNADRD4PTGIRHPGD | |
| SCHEMBL9712008 | 0.82 | PTPN1 (0.36) | POLBSMN1; SMN2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL9711938 | 0.82 | PTPN1 (0.38) | POLBSMN1; SMN2ALDH1A1PTGIR | |
| SCHEMBL9711750 | 0.82 | POLB (0.43) | POLBSMN1; SMN2GLAALDH1A1ADRA2C | |
| SCHEMBL9711940 | 0.82 | PPARA (0.51) | POLBSMN1; SMN2ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL9585387 | 0.81 | ALDH1A1 (0.51) | POLBSMN1; SMN2GLAALDH1A1ADRA2C | |
| SCHEMBL9711767 | 0.81 | ALDH1A1 (0.46) | POLBSMN1; SMN2GLAALDH1A1ADRA2C | |
| SCHEMBL9711754 | 0.80 | POLB (0.43) | POLBSMN1; SMN2GLAALDH1A1ADRA2C | |
| SCHEMBL9585096 | 0.79 | ALDH1A1 (0.51) | POLBSMN1; SMN2GLAALDH1A1ADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0303227-B1 | ETHERS AND THIOETHERS HAVING THERAPEUTICAL ACTIVITY, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1992-02-05 | — | — | EP | disclosed |