Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | SELP | P16109 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711938 | 0.91 | PTPN1 (0.38) | PTPN1PKMTDP1ALDH1A1POLB | |
| SCHEMBL9711860 | 0.84 | PKM (0.51) | HPGDPKMKMT2ATDP1ALDH1A1 | |
| SCHEMBL9711755 | 0.83 | PTPN1 (0.34) | PTPN1ACHEHPGDPKMKMT2A | |
| SCHEMBL9585869 | 0.82 | ACHE (0.41) | PTPN1ACHEHPGDPKMKMT2A | |
| SCHEMBL9711733 | 0.82 | POLB (0.51) | HPGDKMT2AALDH1A1POLBHSD17B10 | |
| SCHEMBL9585086 | 0.80 | ACHE (0.39) | PTPN1ACHEPKMKMT2ATDP1 | |
| SCHEMBL9585454 | 0.80 | ACHE (0.41) | PTPN1ACHEHPGDPKMKMT2A | |
| SCHEMBL3266050 | 0.78 | ALDH1A1 (0.51) | PTPN1ACHEHPGDPKMKMT2A | |
| SCHEMBL3266043 | 0.78 | ALDH1A1 (0.51) | PTPN1ACHEHPGDPKMKMT2A | |
| SCHEMBL10516427 | 0.77 | ACHE (0.36) | PTPN1ACHEHPGDKDM4EPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0303227-B1 | ETHERS AND THIOETHERS HAVING THERAPEUTICAL ACTIVITY, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1992-02-05 | — | — | EP | disclosed |