Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9711940 | 0.85 | PPARA (0.51) | PPARANPC1RAB9AKDM4ETDP1 | |
| SCHEMBL9711750 | 0.82 | POLB (0.43) | TDP1ALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL9712014 | 0.81 | ALDH1A1 (0.51) | PPARANPC1RAB9AKDM4ETDP1 | |
| SCHEMBL9859946 | 0.80 | ALDH1A1 (0.63) | PPARANPC1RAB9AKDM4ETDP1 | |
| SCHEMBL9585770 | 0.78 | ALDH1A1 (0.51) | PPARANPC1RAB9AKDM4ETDP1 | |
| SCHEMBL9711755 | 0.77 | PTPN1 (0.34) | TDP1ALDH1A1MAPTKMT2AGAA | |
| SCHEMBL9712081 | 0.77 | PTPN1 (0.36) | NPC1RAB9ATDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9711718 | 0.76 | PKM (0.49) | TDP1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9584706 | 0.75 | PPARA (0.69) | PPARANPC1RAB9AKDM4ETDP1 | |
| SCHEMBL9711754 | 0.74 | POLB (0.43) | NPC1RAB9AALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0303227-B1 | ETHERS AND THIOETHERS HAVING THERAPEUTICAL ACTIVITY, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1992-02-05 | — | — | EP | disclosed |