Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | MTTP | P55157 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | LSS | P48449 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8837111 | 1.00 | CCR2 (0.56) | CCR2OPRM1OPRD1NPC1RAB9A | |
| SCHEMBL7520262 | 0.87 | CCR2 (0.48) | CCR2NPSR1KDM4ESMN1; SMN2 | |
| SCHEMBL8837220 | 0.87 | CCR2 (0.48) | CCR2NPSR1KDM4ESMN1; SMN2 | |
| SCHEMBL8837195 | 0.85 | NPSR1 (0.55) | CCR2POLBNPSR1KDM4ESMN1; SMN2 | |
| SCHEMBL6813763 | 0.85 | CA12 (0.54) | CCR2OPRM1OPRD1POLBGAA | |
| SCHEMBL8837129 | 0.84 | ALDH1A1 (0.48) | CCR2POLBGAASMN1; SMN2 | |
| SCHEMBL8837177 | 0.81 | CCR2 (0.43) | CCR2OPRM1OPRD1NPC1POLB | |
| SCHEMBL1710436 | 0.79 | CCR2 (0.48) | CCR2NPC1RAB9APOLBGAA | |
| SCHEMBL7522219 | 0.77 | CCR2 (0.43) | CCR2OPRM1OPRD1NPC1RAB9A | |
| SCHEMBL8837212 | 0.77 | KMT2A (0.55) | NPC1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992021648-A1 | AMINO ACID DERIVATIVE ANTICONVULSANT | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1992-12-10 | — | — | WO | disclosed |