Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 3/20 | 0.64 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.64 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.64 |
| ▸ | POLA1 | P09884 | 1/20 | 0.64 |
| ▸ | POLG | P54098 | 1/20 | 0.64 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.45 |
| ▸ | NT5E | P21589 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.38 |
| ▸ | PI4KA | P42356 | 2/20 | 0.36 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.36 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.36 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712231 | 0.84 | FAP (0.54) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL9417160 | 0.83 | SLC22A6 (0.50) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL2107417 | 0.78 | FGFR1 (0.68) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL29391225 | 0.78 | FGFR1 (0.68) | FAPSLC22A6ABCB11POLA1POLG | |
| Adefovir Dipivoxil SCHEMBL29729 | 0.78 | FAP (1.00) | FAPSLC22A6ABCB11POLA1POLG | |
| Adefovir Dipivoxil SCHEMBL29372789 | 0.78 | FAP (1.00) | FAPSLC22A6ABCB11POLA1POLG | |
| Adefovir Dipivoxil SCHEMBL5845498 | 0.78 | FAP (1.00) | FAPSLC22A6ABCB11POLA1POLG | |
| Adefovir Dipivoxil SCHEMBL3646944 | 0.77 | FAP (0.98) | FAPSLC22A6ABCB11POLA1POLG | |
| Adefovir Dipivoxil SCHEMBL3719079 | 0.77 | FAP (0.98) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL9858339 | 0.77 | FGFR1 (0.50) | FAPSLC22A6ABCB11POLA1POLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992009611-A1 | PHARMACEUTICALS | BEECHAM GROUP PLC (GB) | 1992-06-11 | — | — | WO | claimed |