Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAP | Q12884 | 3/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | POLA1 | P09884 | 1/20 | 0.54 |
| ▸ | POLG | P54098 | 1/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.41 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.40 |
| ▸ | NT5E | P21589 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712232 | 0.84 | FAP (0.64) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL9417160 | 0.78 | SLC22A6 (0.50) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL29391225 | 0.78 | FGFR1 (0.68) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL2107417 | 0.78 | FGFR1 (0.68) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL9156685 | 0.73 | SLC22A6 (0.46) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL471810 | 0.73 | SLC22A6 (0.67) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL9858339 | 0.72 | FGFR1 (0.50) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL9857536 | 0.71 | FGFR1 (0.65) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL3720707 | 0.71 | SLC22A6 (0.76) | FAPSLC22A6ABCB11POLA1POLG | |
| SCHEMBL3922476 | 0.71 | ADORA2A (0.50) | SLC22A6FGFR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992009611-A1 | PHARMACEUTICALS | BEECHAM GROUP PLC (GB) | 1992-06-11 | — | — | WO | claimed |