Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 3/20 | 0.48 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.48 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.48 |
| ▸ | PRCP | P42785 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25022773 | 0.86 | GNAI3 (0.48) | GNAI3GNAO1GNAI1PRCPNPSR1 | |
| SCHEMBL25022737 | 0.86 | GNAI3 (0.48) | GNAI3GNAO1GNAI1PRCPNPSR1 | |
| SCHEMBL25021919 | 0.86 | GNAI3 (0.48) | GNAI3GNAO1GNAI1PRCPNPSR1 | |
| SCHEMBL25023038 | 0.82 | GNAI3 (0.52) | GNAI3GNAO1GNAI1PRCPNAAA | |
| SCHEMBL25023495 | 0.82 | GNAI3 (0.52) | GNAI3GNAO1GNAI1PRCPNAAA | |
| SCHEMBL10336963 | 0.82 | CFD (0.37) | NPSR1POLB | |
| SCHEMBL30306891 | 0.80 | GNAI3 (0.50) | GNAI3GNAO1GNAI1PRCPNAAA | |
| SCHEMBL18231595 | 0.79 | CHRNB2 (0.44) | GNAI3GNAO1GNAI1PRCPNPSR1 | |
| SCHEMBL25022230 | 0.79 | GNAI3 (0.46) | GNAI3GNAO1GNAI1PRCPNPSR1 | |
| SCHEMBL28968976 | 0.76 | PRCP (0.67) | PRCPNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992020661-A1 | N, N-DIACYLPIPERAZINES | MERCK & CO., INC. (US) | 1992-11-26 | — | — | WO | disclosed |