Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 2/20 | 0.31 |
| ▸ | GALR3 | O60755 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.30 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618864 | 0.82 | TSHR (0.36) | TSHRSMN1; SMN2LMNAMEN1CYP1A2 | |
| SCHEMBL13684596 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL9712345 | 0.79 | MEN1 (0.37) | MEN1KMT2AGABBR2GABBR1CYP2C19 | |
| Hydrochloric Acid SCHEMBL9712305 | 0.78 | MAPT (0.39) | TSHRLMNAMEN1CYP1A2KMT2A | |
| SCHEMBL24490918 | 0.77 | GAA (0.33) | TSHRSMN1; SMN2LMNAMEN1CYP1A2 | |
| SCHEMBL17155075 | 0.77 | LMNA (0.56) | TSHRSMN1; SMN2LMNAMEN1CYP1A2 | |
| SCHEMBL10603451 | 0.77 | GAA (0.47) | TSHRSMN1; SMN2LMNAMEN1CYP1A2 | |
| SCHEMBL9327606 | 0.77 | CA2 (0.37) | TSHRSMN1; SMN2LMNAMEN1CYP1A2 | |
| Hydrochloric Acid SCHEMBL10711948 | 0.75 | CA2 (0.36) | TSHRSMN1; SMN2GAATDP1CHRM2 | |
| SCHEMBL19361541 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1102055-A | — | — | None | — | — | JP | disclosed |
| EP-0309421-B1 | O-ALKANOYL DERIVATIVES OF 3-AMINO-2-HYDROXYPROPANESULFONIC ACID HAVING ANTICONVULSIVANT ACTIVITY AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME FOR THE THERAPEUTICAL TREATMENT OF EPILEPSY | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. (IT) | 1992-11-19 | — | — | EP | disclosed |
| JP-H01102055-A | O-ALKANOYL DERIVATIVE OF 3-AMINO-2-HYDROXYPROPANESULFONIC ACID | SIGMA TAU IND FARMACEUT RIUNITE SPA | 1989-04-19 | — | — | JP | disclosed |
| EP-0309421-A2 | O-alkanoyl derivatives of 3-amino-2-hydroxypropanesulfonic acid having anticonvulsivant activity and pharmaceutical compositions containing same for the therapeutical treatment of epilepsy | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. (IT) | 1989-03-29 | — | — | EP | disclosed |