SCHEMBL8618864

SCHEMBL8618864

CCC(CS(=O)(=O)O)OC(C)=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
LMNA P02545 2/20 0.35
MEN1 O00255 1/20 0.35
CYP1A2 P05177 1/20 0.35
HRH1 P35367 1/20 0.35
KMT2A Q03164 1/20 0.35
GAA P10253 1/20 0.35
SLC18A3 Q16572 1/20 0.34
PRKCA P17252 2/20 0.33
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM1 P11229 1/20 0.32
TBXA2R P21731 1/20 0.32
GALR3 O60755 1/20 0.31
MAPT P10636 1/20 0.31
BLM P54132 1/20 0.31
SLC22A6 Q4U2R8 1/20 0.31
ALDH1A1 P00352 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20009247 0.82 MEN1 (0.40) LMNAMEN1KMT2AMAPTSLC22A6
SCHEMBL9712340 0.82 TSHR (0.34) TSHRSMN1; SMN2LMNAMEN1CYP1A2
SCHEMBL3288186 0.81 TSHR (0.36) TSHRALDH1A1
SCHEMBL20009245 0.80
SCHEMBL1584634 0.79
SCHEMBL24490918 0.79 GAA (0.33) TSHRSMN1; SMN2LMNAMEN1CYP1A2
SCHEMBL10603451 0.79 GAA (0.47) TSHRSMN1; SMN2LMNAMEN1CYP1A2
SCHEMBL20009246 0.79 PRKCA (0.44) PRKCA
SCHEMBL17155075 0.79 LMNA (0.56) TSHRSMN1; SMN2LMNAMEN1CYP1A2
SCHEMBL10880708 0.78 GLS2 (0.47) PRKCAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180086948-A1 ADHESIVE COMPOSITION, BIO-ELECTRODE, METHOD FOR MANUFACTURING A BIO-ELECTRODE, AND SALT SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-03-29 US disclosed
US-20180072930-A1 ADHESIVE COMPOSITION, BIO-ELECTRODE, AND METHOD FOR MANUFACTURING A BIO-ELECTRODE SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-03-15 US disclosed
US-20170115566-A1 RESIST COMPOSITION, PATTERNING PROCESS, AND BARIUM, CESIUM AND CERIUM SALTS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-04-27 US disclosed
EP-0643690-B1 DESFERRIOXAMINE-B SALTS AND THEIR USE AS ORALLY EFFECTIVE IRON CHELATORS CIBA GEIGY AG (CH) 1998-05-20 EP disclosed
US-5739167-A Desferrioxamine-B salts and their use as orally effective iron chelators NOVARTIS CORPORATION (US) 1998-04-14 US disclosed
US-5663201-A COMPLEXES WITH IRON OR ALUMINUM CIBA-GEIGY CORPORATION (US) 1997-09-02 US disclosed
EP-0643690-A1 DESFERRIOXAMINE-B SALTS AND THEIR USE AS ORALLY EFFECTIVE IRON CHELATORS Novartis AG (CH) 1995-03-22 EP disclosed
WO-1993024451-A1 DESFERRIOXAMINE-B SALTS AND THEIR USE AS ORALLY EFFECTIVE IRON CHELATORS CIBA-GEIGY AG (CH) 1993-12-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170115566-A1 RESIST COMPOSITION, PATTERNING PROCESS, AND BARIUM, CESIUM AND CERIUM SALTS CASR, LIFR, LBR TSHR 508/4885SMN1; SMN2 786/4885LMNA 482/4885
US-20180086948-A1 ADHESIVE COMPOSITION, BIO-ELECTRODE, METHOD FOR MANUFACTURING A BIO-ELECTRODE, AND SALT SLC9A1, FN1, EPCAM TSHR 1721/4885SMN1; SMN2 1214/4885LMNA 2893/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.