Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PMM2 | O15305 | 1/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7620045 | 0.81 | TSHR (0.46) | TSHRTDP1ALDH1A1VCAM1GRIN2D | |
| SCHEMBL10420952 | 0.77 | ALDH1A1 (0.48) | TSHRTDP1ALDH1A1GRIN2DGRIN3B | |
| SCHEMBL2002527 | 0.76 | TDP1 (0.53) | TSHRTDP1ALDH1A1VCAM1HSD17B10 | |
| SCHEMBL9712402 | 0.74 | CES1 (0.34) | TDP1ALDH1A1MAPK1CYP3A4 | |
| SCHEMBL6172008 | 0.74 | ALDH1A1 (0.41) | TSHRTDP1ALDH1A1VCAM1GRIN2D | |
| SCHEMBL5200982 | 0.74 | ALDH1A1 (0.41) | TSHRTDP1ALDH1A1VCAM1GRIN2D | |
| SCHEMBL27897987 | 0.74 | TSHR (0.41) | TSHRTDP1ALDH1A1VCAM1GRIN2D | |
| SCHEMBL9712486 | 0.74 | ALDH1A1 (0.45) | TSHRTDP1ALDH1A1GRIN2DGRIN3B | |
| SCHEMBL2002160 | 0.74 | ALDH1A1 (0.44) | TSHRTDP1ALDH1A1GRIN2DGRIN3B | |
| SCHEMBL18350282 | 0.74 | GRIN2D (0.41) | TSHRTDP1ALDH1A1VCAM1GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |