Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17760823 | 0.86 | TSHR (0.42) | ALDH1A1TSHRTDP1GRIN2DGRIN3B | |
| SCHEMBL11594465 | 0.86 | ALDH1A1 (0.48) | ALDH1A1TSHRTDP1GPR35LMNA | |
| SCHEMBL13982688 | 0.85 | TSHR (0.41) | ALDH1A1TSHRTDP1GRIN2DGRIN3B | |
| SCHEMBL6305 | 0.83 | VCAM1 (0.50) | ALDH1A1TSHRTDP1GRIN2DGRIN3B | |
| SCHEMBL16954397 | 0.83 | ALDH1A1 (0.39) | ALDH1A1TSHRTDP1GRIN2DGRIN3B | |
| SCHEMBL670917 | 0.81 | TSHR (0.58) | ALDH1A1TSHRTDP1GRIN2DGRIN3B | |
| SCHEMBL2355479 | 0.80 | LMNA (0.47) | ALDH1A1VCAM1MEN1KMT2ALMNA | |
| SCHEMBL55225 | 0.78 | GPR35 (0.55) | ALDH1A1TSHRTDP1GPR35HPGD | |
| SCHEMBL2353914 | 0.77 | ALDH1A1 (0.67) | ALDH1A1TSHRTDP1HPGDMEN1 | |
| SCHEMBL10825047 | 0.77 | PMM2 (0.41) | ALDH1A1TSHRTDP1GPR35LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1210335-B1 | AMINOCARBONYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVES, METHOD FOR PRODUCING SAME AND THE USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2005-09-14 | — | — | EP | claimed |
| US-4754034-A | RECORDING MATERIALS, PRESSURE SENSITIVE, THERMOREACTIVE, ELECTROCHROMIC | BAYER AKTIENGESELLSCHAFT (DE) | 1988-06-28 | — | — | US | claimed |
| EP-0180813-B1 | CHROMOGENIC 4,4-DIARYLDIHYDROCHINAZOLONES, THEIR PREPARATION AND USE | BAYER AG (DE) | 1988-06-01 | — | — | EP | claimed |
| EP-0180813-A1 | Chromogenic 4,4-diaryldihydrochinazolones, their preparation and use | BAYER AG (DE) | 1986-05-14 | — | — | EP | claimed |
| US-4006163-A | POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1977-02-01 | — | — | US | claimed |
| US-6355616-B1 | FUNGICIDE OLIGOPEOTIDES | XOMA (US) TECHNOLOGY LTD. | 2002-03-12 | — | — | US | disclosed |
| WO-2001000671-A1 | DERIVATIVE COMPOUNDS | XOMA TECHNOLOGY LTD. (US) | 2001-01-04 | — | — | WO | disclosed |
| US-4968797-A | PRESSURE-COPYABLE THERMOREACTIVE AND ELECTROCHROMIC RECORDING MATERIALS | BAYER AKTIENGESELLSCHAFT (DE) | 1990-11-06 | — | — | US | disclosed |
| US-4754034-A | RECORDING MATERIALS, PRESSURE SENSITIVE, THERMOREACTIVE, ELECTROCHROMIC | BAYER AKTIENGESELLSCHAFT (DE) | 1988-06-28 | — | — | US | disclosed |
| EP-0180813-B1 | CHROMOGENIC 4,4-DIARYLDIHYDROCHINAZOLONES, THEIR PREPARATION AND USE | BAYER AG (DE) | 1988-06-01 | — | — | EP | disclosed |
| EP-0180813-A1 | Chromogenic 4,4-diaryldihydrochinazolones, their preparation and use | BAYER AG (DE) | 1986-05-14 | — | — | EP | disclosed |
| EP-0116884-B1 | NITRO-NAPHTHYLAMINE SULPHONIC ACIDS | BAYER AG (DE) | 1986-04-09 | — | — | EP | disclosed |
| EP-0116884-A1 | Nitro-naphthylamine sulphonic acids | BAYER AG (DE) | 1984-08-29 | — | — | EP | disclosed |
| US-4167392-A | Transfer printing process for hydrophilic fibrous material or blends of hydrophilic and synthetic fibrous material, with reactive disperse dyes | CIBA-GEIGY AG (CH) | 1979-09-11 | — | — | US | disclosed |
| US-4006163-A | POLYESTERS | CIBA-GEIGY CORPORATION (US) | 1977-02-01 | — | — | US | disclosed |