SCHEMBL9712402

SCHEMBL9712402

Cc1c(Cl)ccc([C]=O)c1C

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CES1 P23141 1/20 0.34
ALDH1A1 P00352 1/20 0.33
MAPT P10636 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPK1 P28482 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
AR P10275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11173801 0.84 AR (0.36) CES1ALDH1A1MAPTCYP3A4AR
SCHEMBL9712531 0.80
SCHEMBL2053018 0.79 ALDH1A1 (0.46) ALDH1A1MAPTCYP3A4TDP1AR
SCHEMBL9442680 0.76 TRPV4 (0.43) ALDH1A1AR
SCHEMBL6681654 0.76 ALDH1A1 (0.48) CES1ALDH1A1MAPTCYP3A4MAPK1
SCHEMBL329259 0.75 TDP2 (0.36) CYP3A4
SCHEMBL9712353 0.74 TSHR (0.38) ALDH1A1CYP3A4MAPK1TDP1
Ammonia Solution, Strong SCHEMBL309539 0.73 ALDH1A1 (0.46) CES1ALDH1A1MAPTCYP3A4MAPK1
SCHEMBL9712516 0.71 AR (0.34) AR
SCHEMBL329657 0.70 MAPK1 (0.40) CES1CYP3A4MAPK1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5117057-A Insecticidal N' substituted-N-N'-disubstituted-hydrazines ROHM AND HAAS COMPANY (US) 1992-05-26 US disclosed