Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.44 |
| ▸ | CES1 | P23141 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535090 | 0.81 | CES2 (0.44) | CES2CES1ALDH1A1MAPTGAA | |
| SCHEMBL5140819 | 0.80 | CES2 (0.47) | CES2CES1ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL9712630 | 0.79 | CDC25B (0.54) | ALDH1A1MAPTMEN1KMT2AHPGD | |
| SCHEMBL9712750 | 0.77 | CA2 (0.34) | ALDH1A1SMN1; SMN2MAPTGAATDP1 | |
| SCHEMBL30293901 | 0.76 | CES2 (0.71) | CES2CES1ALDH1A1ALOX15MAPT | |
| SCHEMBL250099 | 0.76 | CES2 (0.71) | CES2CES1ALDH1A1ALOX15MAPT | |
| SCHEMBL9712499 | 0.76 | MAPT (0.46) | CES2CES1ALDH1A1ALOX15SMN1; SMN2 | |
| SCHEMBL31574193 | 0.74 | CES2 (0.68) | CES2CES1ALDH1A1ALOX15MAPT | |
| SCHEMBL27185988 | 0.74 | CES2 (0.68) | CES2CES1ALDH1A1ALOX15MAPT | |
| Hydrochloric Acid SCHEMBL27733532 | 0.74 | CES2 (0.68) | CES2CES1ALDH1A1ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |