Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | GMNN | O75496 | 1/20 | 0.46 |
| ▸ | TTR | P02766 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6212223 | 0.84 | ALDH1A1 (0.47) | MAPTALDH1A1RAB9AKDM4ECYP3A4 | |
| SCHEMBL2355479 | 0.83 | LMNA (0.47) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL5082416 | 0.82 | TTR (0.41) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL3496237 | 0.80 | TDP1 (0.41) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL9712669 | 0.80 | NPSR1 (0.35) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9712388 | 0.76 | CES2 (0.44) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL5140819 | 0.75 | CES2 (0.47) | MAPTALDH1A1MEN1KMT2AHPGD | |
| SCHEMBL9079084 | 0.74 | ALDH1A1 (0.46) | MAPTALDH1A1RAB9AKDM4ECYP3A4 | |
| SCHEMBL11594465 | 0.74 | ALDH1A1 (0.48) | ALDH1A1LMNACYP3A4TSHRGPR35 | |
| SCHEMBL5614002 | 0.74 | LMNA (0.49) | MAPTALDH1A1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |