Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712500 | 0.87 | SRD5A2 (0.44) | ALDH1A1SRD5A2CES2CES1CNR2 | |
| SCHEMBL7266220 | 0.84 | ALDH1A1 (0.60) | ALDH1A1LMNANPC1RAB9ASRD5A2 | |
| SCHEMBL9712611 | 0.83 | ALDH1A1 (0.50) | ALDH1A1LMNANPC1RAB9ASRD5A2 | |
| SCHEMBL9712594 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNANPC1RAB9ASRD5A2 | |
| SCHEMBL9712524 | 0.81 | ALDH1A1 (0.47) | ALDH1A1LMNANPC1RAB9ASRD5A2 | |
| SCHEMBL9712528 | 0.79 | AKR1C3 (0.50) | ALDH1A1LMNANPC1SRD5A2CES2 | |
| SCHEMBL9712450 | 0.79 | CNR1 (0.48) | ALDH1A1LMNANPC1RAB9ASRD5A2 | |
| SCHEMBL11866833 | 0.78 | MAPK13 (0.42) | ALDH1A1LMNANPC1RAB9ACES2 | |
| SCHEMBL9712451 | 0.77 | HTT (0.42) | ALDH1A1LMNANPC1RAB9ASRD5A2 | |
| SCHEMBL9712424 | 0.77 | CES2 (0.47) | ALDH1A1LMNACES2CES1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |