Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.41 |
| ▸ | CES1 | P23141 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9712611 | 0.87 | ALDH1A1 (0.50) | HTTALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL3282179 | 0.85 | ALDH1A1 (0.45) | HTTKDM4EALDH1A1RAB9ANPC1 | |
| SCHEMBL9712500 | 0.83 | SRD5A2 (0.44) | ALDH1A1SRD5A2MAPK1HPGDCES2 | |
| SCHEMBL9712494 | 0.80 | MAPT (0.49) | KDM4ERAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL9712350 | 0.79 | NR4A1 (0.50) | HTTKDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9712427 | 0.77 | ALDH1A1 (0.47) | ALDH1A1RAB9ASMN1; SMN2NPC1SRD5A2 | |
| SCHEMBL910686 | 0.77 | POLB (0.47) | ALDH1A1SMN1; SMN2HPGDMAPTMEN1 | |
| SCHEMBL1821327 | 0.75 | NR4A1 (0.62) | HTTKDM4EALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL9712444 | 0.75 | NR4A1 (0.53) | ALDH1A1RAB9ASRD5A2MAPK1HPGD | |
| SCHEMBL9130311 | 0.75 | NR4A1 (0.61) | HTTKDM4EALDH1A1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |