Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5911523 | 0.86 | CA12 (0.53) | MAPTHPGDPOLBLMNANPC1 | |
| SCHEMBL9712451 | 0.80 | HTT (0.42) | MAPTHPGDLMNANPC1CYP1A2 | |
| SCHEMBL9712500 | 0.80 | SRD5A2 (0.44) | HPGDCA1CA2 | |
| SCHEMBL6864175 | 0.79 | CA12 (0.47) | LMNANPC1CA12CA1CA2 | |
| SCHEMBL2677857 | 0.78 | CES2 (0.53) | MAPTHPGDNPC1CA12CA1 | |
| SCHEMBL17842454 | 0.73 | MAPT (0.68) | MAPTHPGDPOLBLMNANPC1 | |
| SCHEMBL5207406 | 0.73 | CTSD (0.53) | MAPTCA12CA1CA2CA7 | |
| SCHEMBL9712350 | 0.73 | NR4A1 (0.50) | MAPTHPGDPOLBNPC1SMN1; SMN2 | |
| SCHEMBL6210902 | 0.72 | CA12 (0.41) | MAPTHPGDLMNACA12CA1 | |
| SCHEMBL29851511 | 0.72 | CA12 (0.59) | MAPTHPGDLMNANPC1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |