Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3892471 | 0.82 | — | — | |
| SCHEMBL2093550 | 0.77 | TRPV4 (0.41) | KIF11TRPV4CES2 | |
| SCHEMBL10490644 | 0.77 | — | — | |
| SCHEMBL3432404 | 0.73 | CES2 (0.46) | CES2 | |
| SCHEMBL6209867 | 0.73 | KIF11 (0.53) | KIF11 | |
| SCHEMBL9712472 | 0.73 | KIF11 (0.49) | KIF11NFKB1 | |
| SCHEMBL17143848 | 0.72 | DAO (0.38) | KIF11TRPV4CES2 | |
| SCHEMBL10766551 | 0.72 | KDR (0.40) | KIF11TRPV4 | |
| SCHEMBL2140487 | 0.69 | KIF11 (0.41) | KIF11TRPV4 | |
| SCHEMBL6211552 | 0.68 | NOTUM (0.40) | KIF11TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |