SCHEMBL9712475

SCHEMBL9712475

CCc1ccc(C(=O)c2c(C)cccc2C(=O)Cl)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
MAPT P10636 4/20 0.40
GAA P10253 4/20 0.40
AGTR1 P30556 2/20 0.40
EGFR P00533 1/20 0.40
PLK1 P53350 1/20 0.40
CNR1 P21554 1/20 0.40
CNR2 P34972 1/20 0.40
HTT P42858 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
NPC1 O15118 4/20 0.38
POLB P06746 2/20 0.38
LMNA P02545 1/20 0.38
RAB9A P51151 3/20 0.38
KDM4E B2RXH2 1/20 0.38
TAOK1 Q7L7X3 1/20 0.37
TAOK3 Q9H2K8 1/20 0.37
RXFP1 Q9HBX9 1/20 0.37
OPRM1 P35372 1/20 0.36
OPRD1 P41143 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8174286 0.89 GAA (0.36) ALDH1A1MAPTGAAAGTR1EGFR
SCHEMBL9712495 0.88 GAA (0.44) ALDH1A1MAPTGAAPLK1CNR2
SCHEMBL9712837 0.83 ALDH1A1 (0.39) ALDH1A1MAPTHTTSMN1; SMN2NPC1
SCHEMBL27321464 0.82 AKR1C3 (0.46) ALDH1A1MAPTGAAHTTNPC1
SCHEMBL9712453 0.81 LMNA (0.49) ALDH1A1MAPTPLK1HTTSMN1; SMN2
SCHEMBL9712418 0.81 PLK1 (0.49) ALDH1A1MAPTGAAAGTR1PLK1
SCHEMBL11613100 0.80 PLK1 (0.47) ALDH1A1MAPTGAAAGTR1EGFR
SCHEMBL9712437 0.79 CNR1 (0.40) ALDH1A1CNR1CNR2HTTSMN1; SMN2
SCHEMBL9712552 0.79 KMT2A (0.55) ALDH1A1MAPTGAAHTTSMN1; SMN2
Hydrochloric Acid SCHEMBL8177744 0.79 GAA (0.40) ALDH1A1GAAPLK1CNR2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5117057-A Insecticidal N' substituted-N-N'-disubstituted-hydrazines ROHM AND HAAS COMPANY (US) 1992-05-26 US disclosed