SCHEMBL9712554

SCHEMBL9712554

O=C(Cl)c1ccccc1C(=O)c1ccccc1Cl

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.58
CES1 P23141 1/20 0.58
ALDH1A1 P00352 5/20 0.56
RECQL P46063 1/20 0.55
POLB P06746 3/20 0.52
KMT2A Q03164 2/20 0.49
ALOX15 P16050 1/20 0.48
CYP1A2 P05177 1/20 0.46
HPGD P15428 1/20 0.46
CYP2C19 P33261 1/20 0.46
ERCC5 P28715 1/20 0.44
FEN1 P39748 1/20 0.44
RORB Q92753 2/20 0.44
RORC P51449 1/20 0.44
MTNR1A P48039 1/20 0.44
MTNR1B P49286 1/20 0.44
LMNA P02545 1/20 0.44
GAA P10253 1/20 0.44
GABRP O00591 1/20 0.43
GABRD O14764 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3444846 0.91 CES2 (0.68) CES2CES1ALDH1A1RECQLPOLB
Selenium SCHEMBL30382145 0.89 CES2 (0.65) CES2CES1ALDH1A1RECQLPOLB
SCHEMBL50416 0.89 CES2 (0.71) CES2CES1ALDH1A1RECQLPOLB
SCHEMBL29399311 0.89 CES2 (0.71) CES2CES1ALDH1A1RECQLPOLB
SCHEMBL9375700 0.89 ALDH1A1 (0.58) CES2CES1ALDH1A1RECQLPOLB
SCHEMBL93276 0.86 CES2 (0.68) CES2CES1ALDH1A1RECQLPOLB
SCHEMBL28272323 0.86 CES2 (0.68) CES2CES1ALDH1A1RECQLPOLB
SCHEMBL29368196 0.86 CES2 (0.68) CES2CES1ALDH1A1RECQLPOLB
SCHEMBL6143391 0.86 CES2 (0.52) CES2CES1ALDH1A1RECQLPOLB
Phosphine SCHEMBL28793716 0.84 CES2 (0.65) CES2CES1ALDH1A1RECQLPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5117057-A Insecticidal N' substituted-N-N'-disubstituted-hydrazines ROHM AND HAAS COMPANY (US) 1992-05-26 US disclosed