SCHEMBL9712934

SCHEMBL9712934

CC(C)(CCCl)c1nnc(N)o1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14037256 0.78 KDM4E (0.35) KDM4ENPC1RAB9A
SCHEMBL25419135 0.69 KDM4E (0.37) KDM4ENPC1RAB9A
SCHEMBL4080491 0.63 KDM4E (0.33) KDM4ENPC1RAB9A
SCHEMBL18643327 0.61 DPP4 (0.33)
SCHEMBL272220 0.59
SCHEMBL20832857 0.58 TSHR (0.37) KDM4ENPC1RAB9A
SCHEMBL19899533 0.58
Hydrazinecarboxamide SCHEMBL22471913 0.58 LMNA (0.38) KDM4ENPC1RAB9A
SCHEMBL21233435 0.56 DPP4 (0.32)
SCHEMBL1400309 0.54 ALDH1A1 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5086184-A Herbicides DOWELANCO (US) 1992-02-04 US disclosed
US-4943634-A HERBICIDES ELI LILLY AND COMPANY (US) 1990-07-24 US disclosed
US-4801718-A HERBICIDES ELI LILLY AND COMPANY (US) 1989-01-31 US disclosed
US-4636243-A HERBICIDES ISOXAZOLES ELI LILLY AND COMPANY (US) 1987-01-13 US disclosed
US-4515625-A HERBICIDES ELI LILLY AND COMPANY (US) 1985-05-07 US disclosed
EP-0049071-B1 N-ARYLBENZAMIDE DERIVATIVES ELI LILLY AND COMPANY (US) 1984-12-19 EP disclosed
US-4416683-A HERBICIDES ELI LILLY AND COMPANY (US) 1983-11-22 US disclosed
EP-0049071-A1 N-arylbenzamide derivatives ELI LILLY AND COMPANY (US) 1982-04-07 EP disclosed