Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.81 |
| ▸ | POLB | P06746 | 4/20 | 0.81 |
| ▸ | MAPT | P10636 | 4/20 | 0.81 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.81 |
| ▸ | FLT3 | P36888 | 4/20 | 0.80 |
| ▸ | CREB1 | P16220 | 2/20 | 0.79 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.79 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.79 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.79 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.79 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.77 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.77 |
| ▸ | RECQL | P46063 | 1/20 | 0.77 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.76 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.76 |
| ▸ | PTPRS | Q13332 | 1/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.76 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.76 |
| ▸ | AURKA | O14965 | 1/20 | 0.74 |
| ▸ | KDR | P35968 | 1/20 | 0.74 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mosloflavone SCHEMBL29477310 | 1.00 | KDM4E (0.81) | KDM4EPOLBMAPTADORA3FLT3 | |
| SCHEMBL28660389 | 0.91 | KDM4E (0.81) | KDM4EPOLBMAPTADORA3FLT3 | |
| SCHEMBL30606765 | 0.91 | KDM4E (0.81) | KDM4EPOLBMAPTADORA3FLT3 | |
| Cirsimaritin SCHEMBL29459674 | 0.90 | POLB (1.00) | KDM4EPOLBMAPTADORA3FLT3 | |
| Cirsimaritin SCHEMBL1663486 | 0.90 | POLB (1.00) | KDM4EPOLBMAPTADORA3FLT3 | |
| SCHEMBL30152130 | 0.90 | ABCB1 (0.81) | KDM4EPOLBMAPTADORA3FLT3 | |
| SCHEMBL718970 | 0.90 | ABCB1 (0.81) | KDM4EPOLBMAPTADORA3FLT3 | |
| SCHEMBL15674607 | 0.90 | ABCB1 (0.81) | KDM4EPOLBMAPTADORA3FLT3 | |
| Baicalein Trimethyl Ether SCHEMBL971297 | 0.89 | ABCB1 (0.80) | KDM4EPOLBMAPTADORA3FLT3 | |
| SCHEMBL18828144 | 0.89 | FLT3 (0.71) | KDM4EPOLBMAPTADORA3FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113736804-B | Baical skullcap flavone methoxy transferase gene, recombinant vector and application thereof | 上海辰山植物园 | 2023-09-22 | — | — | CN | claimed |
| CN-105669625-A | 2-substituted benzopyran-4-one compounds and application thereof | 中国人民解放军第二军医大学 | 2016-06-15 | — | — | CN | claimed |
| EP-4580594-A1 | ANTIOXIDANT COMPOSITION COMPRISING 5-DEOXYFLAVONOIDS | AnalytiCon Discovery - Zweigniederlassung der BRAIN Biotech AG (DE) | 2025-07-09 | — | — | EP | disclosed |
| US-20240299464-A1 | BOTANICAL COMPOUNDS, METHODS, AND PROCEDURES FOR MEDICINAL TREATMENT RELATED TO IMMUNOINFLAMMATION, NEUROINFLAMMATION, DEPRESSION, MEMORY, FOCUS, AND NERVE DEGENERATION | NGUYEN MINH H (US) | 2024-09-12 | — | — | US | disclosed |
| WO-2024173722-A2 | BOTANICAL COMPOUNDS, METHODS, AND PROCEDURES FOR MEDICINAL TREATMENT RELATED TO IMMUNOINFLAMMATION, NEUROINFLAMMATION, DEPRESSION, MEMORY, FOCUS, AND NERVE DEGENERATION | NGUYEN MINH H (US) | 2024-08-22 | — | — | WO | disclosed |
| CN-117379469-B | Application of rosewood heart wood extract | 珠海市食品药品检验所 | 2024-04-16 | — | — | CN | disclosed |
| WO-2024046834-A1 | ANTIOXIDANT COMPOSITION COMPRISING 5-DEOXYFLAVONOIDS | ANALYTICON DISCOVERY GMBH (DE) | 2024-03-07 | — | — | WO | disclosed |
| EP-4331564-A1 | ANTIOXIDANT COMPOSITION COMPRISING 5-DEOXYFLAVONOIDS | Analyticon Discovery GmbH (DE) | 2024-03-06 | — | — | EP | disclosed |
| CN-117379469-A | Application of rosewood heart wood extract | 珠海市食品药品检验所 | 2024-01-12 | — | — | CN | disclosed |
| US-11812774-B2 | Composition for browning inhibition and use of same | SUNTORY HOLDINGS LIMITED (JP) | 2023-11-14 | — | — | US | disclosed |
| US-11812774-B2 | Composition for browning inhibition and use of same | SUNTORY HOLDINGS LIMITED (JP) | 2023-11-14 | — | — | US | disclosed |
| CN-104922103-A | Application of mosloflavone in preparation of anti hypoxic drugs | MA HUIPING | 2015-09-23 | — | — | CN | disclosed |
| CN-104585255-A | Mosquito-repelling bactericide | LIU XIANGSHANG | 2015-05-06 | — | — | CN | disclosed |
| CN-104586873-A | Application of oroxin A in preparation of medicines for treating cancer | UNIV SOOCHOW | 2015-05-06 | — | — | CN | disclosed |
| CN-104431901-A | Pickling method of Indian trumetflower seeds | PU ER MENGYEJIANG AGRICULTURE FOOD DEV CO LTD | 2015-03-25 | — | — | CN | disclosed |
| CN-103622866-B | Perfume capable of whitening and preparation method thereof | GOLD ONYX PERFUME MINGGUANG CO LTD | 2015-03-04 | — | — | CN | disclosed |
| CN-103622866-A | Perfume capable of whitening and preparation method thereof | AGATE PERFUME MINGGUANG CO LTD | 2014-03-12 | — | — | CN | disclosed |
| US-7875650-B2 | Baicalein analogs; enhances bioavailability of active compounds, especially orally administered compounds, by inhibition of P-glycoprotein 170 (P-gp 170) and/or CYP450 enzyme; 6-Acetoxy-5,7-dihydroxyflavone | YALE UNIVERSITY (US) | 2011-01-25 | — | — | US | disclosed |
| US-20070161605-A1 | Compounds and methods to increase anti-p-glycoprotein activity of baicalein by alkylation on the a ring | YALE UNIVERSITY (US) | 2007-07-12 | — | — | US | disclosed |
| WO-2005075449-A1 | COMPOUNDS AND METHODS TO INCREASE ANTI-P-GLYCOPROTEIN ACTIVITY OF BAICALEIN BY ALKYLATION ON THE A RING | YALE UNIVERSITY (US) | 2005-08-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070161605-A1 | Compounds and methods to increase anti-p-glycoprotein activity of baicalein by alkylation on the a ring | ABCB1, ABCB11, ABCG2 | KDM4E 2696/4885POLB 593/4885MAPT 4867/4885 |
| US-11812774-B2 | Composition for browning inhibition and use of same | MT-CO1, COX6B1, ARG2 | KDM4E 1866/4885POLB 1815/4885MAPT 4484/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.