Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13730194 | 0.84 | RAB9A (0.43) | KDM4ECYP1A2CYP2C19CYP3A4ALDH1A1 | |
| SCHEMBL10969527 | 0.83 | KDM4E (0.72) | KDM4ECYP1A2CYP2C19CYP3A4ALDH1A1 | |
| SCHEMBL11507796 | 0.83 | CYP1A2 (0.54) | CYP1A2CYP2C19CYP3A4ALDH1A1MEN1 | |
| SCHEMBL13584626 | 0.83 | KMT2A (0.46) | KDM4ECYP1A2CYP2C19CYP3A4ALDH1A1 | |
| SCHEMBL11508811 | 0.83 | CYP2C19 (0.48) | CYP1A2CYP2C19CYP3A4ALDH1A1MEN1 | |
| SCHEMBL9647774 | 0.82 | NPSR1 (0.51) | KDM4ECYP1A2CYP2C19CYP3A4ALDH1A1 | |
| SCHEMBL9837649 | 0.79 | LPAR2 (0.58) | KDM4EALDH1A1KMT2AMAPT | |
| SCHEMBL11901010 | 0.79 | LMNA (0.69) | KDM4ECYP1A2CYP2C19CYP3A4ALDH1A1 | |
| SCHEMBL29563496 | 0.78 | HDAC3 (0.75) | KDM4ECYP1A2CYP2C19CYP3A4ALDH1A1 | |
| SCHEMBL5944841 | 0.78 | HDAC3 (0.75) | KDM4ECYP1A2CYP2C19CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017476-A1 | BENZOYLPHENYL PYRIDINYLTHIAZOLIDINE COMPOUNDS AS PLATELET ACTIVATING ANTAGONISTS | ABBOTT LABORATORIES (US) | 1992-10-15 | — | — | WO | disclosed |