Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2676735 | 0.84 | MAPK14 (0.37) | KDM4EALDH1A1MAPTBLMCNR2 | |
| SCHEMBL1013262 | 0.82 | CNR2 (0.30) | KDM4EALDH1A1MAPTBLMCNR2 | |
| SCHEMBL431491 | 0.79 | ALDH1A1 (0.42) | KDM4EALDH1A1MAPTBLMCNR2 | |
| SCHEMBL24959709 | 0.78 | KDM4E (0.30) | KDM4EALDH1A1MAPTBLM | |
| SCHEMBL22796278 | 0.78 | TRPM8 (0.35) | ALDH1A1MAPTCNR2 | |
| SCHEMBL13391465 | 0.77 | HMGCR (0.33) | — | |
| SCHEMBL11249883 | 0.76 | — | — | |
| SCHEMBL17796648 | 0.75 | CYP1A2 (0.38) | KDM4EALDH1A1MAPTBLMCNR2 | |
| SCHEMBL1012674 | 0.75 | BRD4 (0.33) | KDM4EALDH1A1MAPTBLM | |
| SCHEMBL1012946 | 0.75 | ALDH1A1 (0.33) | KDM4EALDH1A1MAPTBLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103772308-B | (preparation method of 1-ethyl-1-methyl-propyl) isoxazole intermediate is with the preparation method of Yi Evil grass amine for 5-amino-3- | BEIJING NUTRICHEM COMPANY LIMITED (CN) | 2015-11-18 | — | — | CN | claimed |
| CN-103772308-A | Preparation method of 5-amino-3-(1-ethyl-1-methyl propyl) isoxazole midbody and preparation method of isoxaben | NUTRICHEM CO LTD | 2014-05-07 | — | — | CN | claimed |
| WO-2023288253-A1 | SMALL MOLECULES INHIBITORS OF CYCLIC GMP-AMP SYNTHASE (CGAS) | THE SCRIPPS RESEARCH INSTITUTE (US) | 2023-01-19 | — | — | WO | disclosed |
| CN-103772308-B | (preparation method of 1-ethyl-1-methyl-propyl) isoxazole intermediate is with the preparation method of Yi Evil grass amine for 5-amino-3- | BEIJING NUTRICHEM COMPANY LIMITED (CN) | 2015-11-18 | — | — | CN | disclosed |
| CN-103772308-A | Preparation method of 5-amino-3-(1-ethyl-1-methyl propyl) isoxazole midbody and preparation method of isoxaben | NUTRICHEM CO LTD | 2014-05-07 | — | — | CN | disclosed |
| CN-103772308-A | Preparation method of 5-amino-3-(1-ethyl-1-methyl propyl) isoxazole midbody and preparation method of isoxaben | NUTRICHEM CO LTD | 2014-05-07 | — | — | CN | disclosed |
| CN-103772308-A | Preparation method of 5-amino-3-(1-ethyl-1-methyl propyl) isoxazole midbody and preparation method of isoxaben | NUTRICHEM CO LTD | 2014-05-07 | — | — | CN | disclosed |
| US-5086184-A | Herbicides | DOWELANCO (US) | 1992-02-04 | — | — | US | disclosed |
| US-4943634-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1990-07-24 | — | — | US | disclosed |
| US-4801718-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1989-01-31 | — | — | US | disclosed |
| US-4636243-A | HERBICIDES ISOXAZOLES | ELI LILLY AND COMPANY (US) | 1987-01-13 | — | — | US | disclosed |
| US-4515625-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1985-05-07 | — | — | US | disclosed |
| EP-0049071-B1 | N-ARYLBENZAMIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1984-12-19 | — | — | EP | disclosed |
| US-4416683-A | HERBICIDES | ELI LILLY AND COMPANY (US) | 1983-11-22 | — | — | US | disclosed |
| EP-0049071-A1 | N-arylbenzamide derivatives | ELI LILLY AND COMPANY (US) | 1982-04-07 | — | — | EP | disclosed |