Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 4/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | PELI1 | Q96FA3 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713478 | 0.95 | ESR1 (0.51) | BACE1ESR1ESR2MAPTKDM4E | |
| SCHEMBL9713335 | 0.95 | ESR1 (0.51) | LTA4HBACE1ESR1ESR2MEN1 | |
| SCHEMBL23861344 | 0.84 | ESR2 (0.62) | BACE1ESR1ESR2PELI1ALDH1A1 | |
| SCHEMBL835714 | 0.83 | ESR1 (0.66) | BACE1ESR1ESR2PELI1ALDH1A1 | |
| SCHEMBL30174968 | 0.83 | ESR1 (0.66) | BACE1ESR1ESR2PELI1ALDH1A1 | |
| SCHEMBL9817035 | 0.82 | BACE1 (0.53) | BACE1MAPTKDM4EMAPK1SMN1; SMN2 | |
| SCHEMBL9713660 | 0.81 | ESR2 (0.59) | BACE1ESR1ESR2MAPTKDM4E | |
| SCHEMBL23861365 | 0.81 | ESR2 (0.59) | BACE1ESR1ESR2MAPTKDM4E | |
| 1,4-Dimethoxybenzene SCHEMBL7460138 | 0.81 | BACE1 (0.59) | LTA4HBACE1ESR1ESR2MAPT | |
| SCHEMBL9713538 | 0.80 | ESR1 (0.48) | LTA4HBACE1ESR1ESR2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0249963-B1 | POLYCARBONATES | IDEMITSU KOSAN COMPANY LIMITED (JP) | 1992-04-22 | — | — | EP | claimed |