SCHEMBL9713478

SCHEMBL9713478

COc1ccc(C(C)(c2ccc(O)c(-c3ccccc3)c2)c2ccc(O)c(-c3ccccc3)c2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.51
ESR2 Q92731 2/20 0.51
BACE1 P56817 4/20 0.51
KDM4E B2RXH2 2/20 0.44
MAPT P10636 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
MAPK1 P28482 1/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
POLB P06746 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
PDE4B Q07343 2/20 0.43
PELI1 Q96FA3 1/20 0.43
NCOA1 Q15788 1/20 0.42
NCOA3 Q9Y6Q9 1/20 0.42
ABL1 P00519 1/20 0.41
ABCB1 P08183 1/20 0.41
BCR P11274 1/20 0.41
HDAC4 P56524 2/20 0.41
HDAC2 Q92769 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9713261 0.95 LTA4H (0.47) ESR1ESR2BACE1KDM4EMAPT
SCHEMBL23861344 0.89 ESR2 (0.62) ESR1ESR2BACE1PDE4BPELI1
SCHEMBL9713335 0.88 ESR1 (0.51) ESR1ESR2BACE1MEN1KMT2A
SCHEMBL30174968 0.88 ESR1 (0.66) ESR1ESR2BACE1PDE4BPELI1
SCHEMBL835714 0.88 ESR1 (0.66) ESR1ESR2BACE1PDE4BPELI1
SCHEMBL9817035 0.87 BACE1 (0.53) BACE1KDM4EMAPTSMN1; SMN2MAPK1
SCHEMBL9713660 0.86 ESR2 (0.59) ESR1ESR2BACE1KDM4EMAPT
SCHEMBL23861365 0.86 ESR2 (0.59) ESR1ESR2BACE1KDM4EMAPT
SCHEMBL9713538 0.85 ESR1 (0.48) ESR1ESR2BACE1KDM4EMAPT
SCHEMBL22317286 0.84 ESR2 (0.61) ESR1ESR2BACE1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0249963-B1 POLYCARBONATES IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-04-22 EP claimed
EP-0249963-A2 Polycarbonates IDEMITSU KOSAN COMPANY LIMITED (JP) 1987-12-23 EP claimed
US-5151531-A DIHYDRIC PHENOLS IDEMITSU KOSAN CO., LTD. (JP) 1992-09-29 US disclosed
EP-0249963-B1 POLYCARBONATES IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-04-22 EP disclosed
EP-0277627-B1 POLYFORMAL RESINS AND PROCESS FOR PRODUCING SAID RESINS IDEMITSU KOSAN COMPANY LIMITED (JP) 1991-10-23 EP disclosed
US-4892924-A Polycarbonate containing compound from bis(3-phenyl-4-hydroxyphenyl) IDEMITSU KOSAN CO., LTD. (JP) 1990-01-09 US disclosed
US-4801679-A Polyformal resin and process for producing said resin IDEMITSU KOSAN CO., LTD. (JP) 1989-01-31 US disclosed
EP-0277627-A1 Polyformal resins and process for producing said resins IDEMITSU KOSAN COMPANY LIMITED (JP) 1988-08-10 EP disclosed
EP-0249963-A2 Polycarbonates IDEMITSU KOSAN COMPANY LIMITED (JP) 1987-12-23 EP disclosed