Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.38 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.38 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.38 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627415 | 0.86 | TOP2A (0.49) | TOP2AALOX15CNR2KDM4EPPARG | |
| SCHEMBL9642996 | 0.85 | L3MBTL1 (0.44) | TOP2AALOX15L3MBTL1CNR2KDM4E | |
| SCHEMBL9713991 | 0.83 | ALOX15 (0.41) | TOP2AALOX15HTR1AHTR1BPPARG | |
| SCHEMBL9642678 | 0.81 | L3MBTL1 (0.41) | TOP2AALOX15L3MBTL1CNR2KDM4E | |
| SCHEMBL9714009 | 0.81 | MAPT (0.46) | TOP2AALOX15CNR2KDM4EKMT2A | |
| SCHEMBL9642831 | 0.80 | L3MBTL1 (0.40) | TOP2AALOX15L3MBTL1CNR2KDM4E | |
| SCHEMBL9642101 | 0.80 | L3MBTL1 (0.40) | TOP2AALOX15L3MBTL1CNR2KDM4E | |
| SCHEMBL15557848 | 0.79 | ALOX15 (0.60) | TOP2AALOX15L3MBTL1CNR2KDM4E | |
| SCHEMBL10522637 | 0.79 | KMT2A (0.40) | TOP2AALOX15L3MBTL1CNR2KDM4E | |
| SCHEMBL9643103 | 0.79 | L3MBTL1 (0.41) | TOP2AALOX15L3MBTL1CNR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |