Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB11 | O95342 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | LDHA | P00338 | 1/20 | 0.37 |
| ▸ | LDHB | P07195 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9627724 | 0.84 | ALOX5 (0.48) | ABCB11HTTMAPTLDHALDHB | |
| SCHEMBL9627592 | 0.82 | ABCB11 (0.51) | ABCB11ALDH1A1KDM4ENPC1HPGD | |
| SCHEMBL9627596 | 0.78 | KDM4E (0.51) | ALDH1A1KDM4ESMN1; SMN2HTTMAPT | |
| SCHEMBL9643010 | 0.76 | ABCB11 (0.65) | ABCB11ALDH1A1MEN1KMT2AALOX5 | |
| SCHEMBL30434152 | 0.76 | ABCB11 (0.53) | ABCB11ALDH1A1KDM4ENPC1HPGD | |
| SCHEMBL20398581 | 0.76 | ABCB11 (0.53) | ABCB11ALDH1A1KDM4ENPC1HPGD | |
| SCHEMBL20398612 | 0.76 | ABCB11 (0.53) | ABCB11ALDH1A1KDM4ENPC1HPGD | |
| SCHEMBL9641994 | 0.75 | ABCB11 (0.63) | ABCB11ALDH1A1MEN1KMT2AALOX5 | |
| SCHEMBL9642059 | 0.75 | ABCB11 (0.63) | ABCB11ALDH1A1MEN1KMT2AALOX5 | |
| SCHEMBL9629355 | 0.75 | LDHA (0.48) | ABCB11ALDH1A1KDM4ESMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |