Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.34 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.34 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.34 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.34 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.34 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.34 |
| ▸ | S100A4 | P26447 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 2/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | CDC25A | P30304 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9641764 | 0.84 | S100A4 (0.34) | ALDH1A1MAPK1PSEN1PSEN2APH1B | |
| SCHEMBL9643210 | 0.83 | ALDH1A1 (0.40) | ALDH1A1MAPK1S100A4MAPTCDC25B | |
| SCHEMBL9713322 | 0.82 | PTPN1 (0.41) | ALDH1A1MAPK1S100A4MAPTCDC25B | |
| SCHEMBL9713336 | 0.81 | PTPN1 (0.40) | MAPK1S100A4MAPTPTPN1SOAT1 | |
| SCHEMBL9713511 | 0.79 | S100A4 (0.41) | S100A4MAPTCDC25BPTPRCL3MBTL1 | |
| SCHEMBL9629343 | 0.79 | CDC25B (0.51) | S100A4CDC25BPTPRCIDO1CDC25A | |
| SCHEMBL9713515 | 0.79 | CDC25B (0.36) | ALDH1A1S100A4CDC25BPTPRCIDO1 | |
| SCHEMBL9713605 | 0.76 | S100A4 (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9714061 | 0.74 | S100A4 (0.38) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9713781 | 0.73 | S100A4 (0.40) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |