Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.41 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.39 |
| ▸ | TUBB | P07437 | 2/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.39 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.39 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713934 | 0.84 | ABCB11 (0.49) | HTTABCB11TNFSF11NQO1TUBB4A | |
| SCHEMBL9641644 | 0.83 | ABCB11 (0.60) | HTTABCB11TNFSF11TUBB4ATUBB | |
| SCHEMBL9713479 | 0.83 | HTT (0.40) | HTTABCB11TNFSF11NQO1TUBB4A | |
| SCHEMBL9713648 | 0.81 | HTT (0.41) | HTTABCB11TNFSF11NQO1TUBB4A | |
| SCHEMBL9627729 | 0.79 | TUBB4A (0.54) | HTTABCB11TNFSF11NQO1TUBB4A | |
| SCHEMBL9627541 | 0.79 | HTT (0.51) | HTTABCB11TNFSF11NQO1TUBB4A | |
| SCHEMBL9642914 | 0.79 | ABCB11 (0.51) | HTTABCB11TUBB4ATUBBTUBA3C | |
| SCHEMBL9627435 | 0.78 | HTT (0.47) | HTTABCB11TNFSF11NQO1TUBB4A | |
| SCHEMBL9629306 | 0.78 | ABCB11 (0.68) | HTTABCB11TNFSF11NQO1TUBB4A | |
| SCHEMBL9627790 | 0.78 | HTT (0.47) | HTTABCB11TNFSF11NQO1TUBB4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |