Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.37 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.37 |
| ▸ | USP8 | P40818 | 2/20 | 0.36 |
| ▸ | USP7 | Q93009 | 2/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 3/20 | 0.33 |
| ▸ | STS | P08842 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | TOP2A | P11388 | 1/20 | 0.33 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.33 |
| ▸ | USP47 | Q96K76 | 1/20 | 0.33 |
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25381889 | 0.79 | CASP3 (0.41) | CASP3CA1CA2MALT1MAOB | |
| SCHEMBL28401108 | 0.77 | CASP3 (0.52) | CASP3CA1CA2USP8USP7 | |
| SCHEMBL11621386 | 0.77 | CASP3 (0.52) | CASP3CA1CA2USP8USP7 | |
| SCHEMBL8773066 | 0.76 | S100A4 (0.56) | AURKAAURKBUSP8USP7USP47 | |
| SCHEMBL9713531 | 0.76 | IDO1 (0.56) | CASP3USP8MALT1STSTP53 | |
| SCHEMBL27087501 | 0.74 | CASP3 (0.44) | CASP3CA1CA2VCAM1MALT1 | |
| SCHEMBL11622088 | 0.73 | CASP3 (0.52) | CASP3CA1CA2USP8USP7 | |
| SCHEMBL9628309 | 0.73 | S100A4 (0.52) | CA1CA2AURKAAURKB | |
| SCHEMBL7815913 | 0.73 | MAOA (0.53) | CA1CA2AURKAAURKBUSP8 | |
| SCHEMBL30002710 | 0.73 | MAOA (0.53) | CA1CA2AURKAAURKBUSP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |