Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | BAX | Q07812 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL237878 | 0.91 | CA4 (0.43) | LTA4HTSHRMAOANR1H2BAX | |
| SCHEMBL2783392 | 0.83 | MMP1 (0.47) | TSHRCA1CA2CA9 | |
| SCHEMBL28620636 | 0.83 | CYP1A2 (0.48) | NPC1RAB9ACA1CA2LMNA | |
| SCHEMBL10902380 | 0.80 | ALDH1A1 (0.43) | MEN1KMT2AMAOBPGRSMN1; SMN2 | |
| SCHEMBL9421959 | 0.75 | LTA4H (0.50) | LTA4HTSHRMAOANR1H2BAX | |
| SCHEMBL3893562 | 0.75 | LTA4H (0.92) | LTA4HTSHRMAOANR1H2BAX | |
| SCHEMBL122719 | 0.75 | LTA4H (0.92) | LTA4HTSHRMAOANR1H2BAX | |
| SCHEMBL9212518 | 0.75 | LTA4H (0.92) | LTA4HTSHRMAOANR1H2BAX | |
| SCHEMBL22129853 | 0.75 | LTA4H (0.92) | LTA4HTSHRMAOANR1H2BAX | |
| SCHEMBL11576945 | 0.75 | LTA4H (0.92) | LTA4HTSHRMAOANR1H2BAX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246713-B1 | INTERMEDIATES FOR THE PRODUCTION OF NITROGEN-CONTAINING SUBSTITUTED HETEROCYCLIC COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1992-03-04 | — | — | EP | claimed |