Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.37 |
| ▸ | CDC25B | P30305 | 2/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 10/20 | 0.36 |
| ▸ | S100A4 | P26447 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | CDC25A | P30304 | 1/20 | 0.35 |
| ▸ | GAPDH | P04406 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.33 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9642365 | 0.85 | MAPT (0.39) | PTPN1MEN1POLBKMT2AS1PR1 | |
| SCHEMBL9713331 | 0.79 | SLC6A4 (0.39) | SOAT1S100A4 | |
| SCHEMBL9713222 | 0.78 | PTPN1 (0.38) | PTPN1CDC25BPTPRCSOAT1S100A4 | |
| SCHEMBL9628020 | 0.76 | CDC25B (0.59) | PTPN1CDC25BPTPRCSOAT1S100A4 | |
| SCHEMBL9714218 | 0.76 | NPC1 (0.36) | PTPN1SOAT1 | |
| SCHEMBL9643210 | 0.73 | ALDH1A1 (0.40) | PTPN1CDC25BPTPRCS100A4IDO1 | |
| SCHEMBL9444193 | 0.72 | CDC25B (0.57) | PTPN1CDC25BPTPRCSOAT1S100A4 | |
| Naphthoquinone SCHEMBL28157298 | 0.72 | CDC25B (0.53) | PTPN1CDC25BPTPRCSOAT1S100A4 | |
| SCHEMBL11247136 | 0.71 | CDC25B (0.56) | PTPN1CDC25BPTPRCSOAT1S100A4 | |
| SCHEMBL9628579 | 0.71 | CDC25B (0.56) | PTPN1CDC25BPTPRCSOAT1S100A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |