Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
| ▸ | BCL2 | P10415 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 3/20 | 0.35 |
| ▸ | S100A4 | P26447 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9713415 | 0.84 | BCL2 (0.39) | BCL2MCL1SOAT1S100A4MAPT | |
| SCHEMBL9713644 | 0.79 | PTPN1 (0.37) | SOAT1S100A4 | |
| SCHEMBL9713573 | 0.75 | MAOA (0.55) | BCL2MCL1S100A4 | |
| SCHEMBL9642365 | 0.73 | MAPT (0.39) | BCL2MCL1CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL9713724 | 0.73 | L3MBTL1 (0.50) | BCL2MCL1CYP2C9CYP2C19CYP2D6 | |
| SCHEMBL9713334 | 0.72 | MCL1 (0.57) | BCL2MCL1S100A4 | |
| SCHEMBL9713721 | 0.72 | P4HB (0.44) | BCL2MCL1L3MBTL1 | |
| SCHEMBL9713712 | 0.71 | DDAH1 (0.41) | BCL2MCL1 | |
| SCHEMBL9627363 | 0.71 | SMN1; SMN2 (0.56) | SOAT1S100A4SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL9713584 | 0.71 | IDO1 (0.52) | BCL2MCL1S100A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091558-A | Topical administeration | SYNTEX (U.S.A.) INC. (US) | 1992-02-25 | — | — | US | disclosed |
| EP-0150831-B1 | NAPHTHALENE ANTI-PSORIATIC AGENTS | SYNTEX (U.S.A.) INC. (US) | 1988-08-10 | — | — | EP | disclosed |
| EP-0150831-A2 | Naphthalene anti-psoriatic agents | SYNTEX (U.S.A.) INC. (US) | 1985-08-07 | — | — | EP | disclosed |